Degenerative myelopathy (DM) is a debilitating disease that unfortunately also affects the Saarlooswoldogs, a beautiful breed known for its wolf-like appearance and gentle nature. Although the condition often goes unnoticed initially, it can eventually lead to paralysis, which can have a devastating impact on the dog's quality of life. In this article, we discuss what DM is, how it affects Saarlooswolfdogs, its heredity, and what breeders should do to prevent this disease.

What is Degenerative Myelopathy?

Degenerative myelopathy (DM) is a progressive neurological disorder affecting the spinal cord. In dogs suffering from DM, the nerve cells in the spinal cord slowly die, resulting in loss of motor functions, mainly in the hind legs. The disease usually starts with mild problems such as shaky walking or stumbling, but over months or years the condition worsens to complete paralysis of the hind legs. Eventually, the disease can also affect the front legs and lead to breathing problems, often making euthanasia inevitable.

Although DM does not cause pain, the progressive paralysis associated with it is very profound. The condition is often compared to amyotrophic lateral sclerosis (ALS) in humans because of its similar impact on the nervous system.

Degenerative myelopathy and the Saarlooswolfdog

The Saarlooswolfdog, a breed with a fascinating history and genetic background, is unfortunately susceptible to DM. This makes it all the more important that breeders, be aware of the risks and take proactive steps to minimise the spread of this disease within the breed.

In many cases, DM in Saarlooswolfdogs is not diagnosed until symptoms are already evident. This can lead to a great shock for owners, especially considering the life expectancy and vitality of the breed. Saarlooswolfdogs are usually active and lively, and seeing a beloved dog struggle to walk can be heartbreaking.

Heredity and genetic testing

DM is an inherited disorder that is transmitted through a recessive gene. This means that both parents must carry the gene to pass it on to their offspring. A dog can be a carrier of the DM gene without ever developing symptoms itself. In fact, dogs can be "free", "carrier" or "sufferer". A dog that is free does not have the gene and therefore cannot pass it on to its offspring. Carriers have one copy of the mutated gene but show no symptoms. Sufferers have two copies of the gene and are likely to develop the disease.

Genetic testing is an important tool in controlling DM within the Saarlooswolfdog breed. By testing both parent dogs before breeding, breeders can determine if there is a risk of offspring developing DM. Ideally, only dogs that are free of the DM gene should be bred, but in some cases, carriers can also be bred as long as they are combined with a free dog so that the pups themselves are not at risk of becoming sufferers.

At Del Urlando Lupo, we take these tests very seriously. Our dogs are thoroughly screened before being used in breeding programmes. This not only helps ensure healthy puppies, but also helps preserve the breed's genetic diversity, which is essential for the long-term health of Saarlooswolfdogs.

Symptoms of DM

The symptoms of degenerative myelopathy may vary depending on the stage of the disease, but the following signs may indicate the onset of the condition:

Difficulty walking, especially in the hind legs
Dragging sound of nails on the ground
Unsteady or unsteady walking
Loss of bladder and bowel control in later stages
Progressieve verlamming van de achterpoten
In de vroege stadia worden de symptomen soms verward met artritis of andere gewrichtsproblemen, wat can make it difficult to make a timely diagnosis. A vet will often perform a comprehensive neurological examination and may recommend a genetic test if DM is suspected.

Treatment and Quality of Life

Unfortunately, there is no cure for degenerative myelopathy. The disease is progressive and eventually leads to paralysis. However, there are ways to improve an affected dog's quality of life. For example, regular physiotherapy can help keep muscles strong for as long as possible. In addition, aids such as harnesses and wheelchairs can improve a dog's mobility, allowing them to continue living an active life even as the disease progresses.

It is also important to adapt the dog's environment so that he can move around safely and comfortably. Non-slip mats can help prevent slipping, and raised food bowls make eating easier for dogs that lose their balance.

Prevention: The Role of Responsible Breeding

The key to preventing DM in Saarlooswolfdogs lies in responsible breeding. This means that breeders, should perform genetic tests on their breeding stock and select only dogs that are free of the DM gene, or in some cases combine carriers with free dogs to eliminate the risk of sufferer puppies.

Our breeding programmes are aimed at ensuring the health of our Saarlooswolfdogs without compromising their vitality and temperament. Screening for DM, as well as other genetic disorders, is essential to secure the future of this special breed.

**Conclusion**

Degenerative myelopathy is a serious condition that can have a major impact on the quality of life of Saarlooswolfdogs and their owners. Although there is no cure, early diagnosis and careful selection of breeding stock can help limit the spread of this disease within the breed. At Del Urlando Lupo, we make every effort to ensure that our dogs are not only beautiful and healthy, but also free of genetic disorders such as DM.